Blimp1 glycosylation
WebSDS-Page: Recombinant Human BLIMP1/PRDM1 Protein [H00000639-Q01] - 12.5% SDS-PAGE Stained with Coomassie Blue. Product Details. Summary. Reactivity: Hu Species Glossary: ... Glycosylation : Research Areas for BLIMP1/PRDM1 Partial Recombinant Protein (H00000639-Q01) Find related products by research area. Cancer; … WebJan 30, 2024 · A hallmark of Niemann-Pick disease, type C (NPC) is the progressive degeneration of Purkinje neurons in the cerebellum caused by the accumulation of free cholesterol and glycosphingolipids in the lysosome. Recent studies suggest that the state of glycosylation of lysosomal membrane proteins may play a role in disease progression. …
Blimp1 glycosylation
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As a potent repressor of beta-interferon (IFN-β), BLIMP-1 competes for interferon regulatory factors (IRF) binding sites in the IFN-β promoter due to its sequence similarity with IRF1 and IRF2. However, BLIMP-1 cools down and activates immune responses in a highly contextual manner. BLIMP-1 represses NFκB/TNF-R pathway repressor NLRP12, thus indirectly activating the immun… WebOct 1, 2024 · BLIMP1 is a transcriptional repressor as its ectopic expression extinguishes …
WebJun 1, 2024 · The glycosylation of PD-1 is essential for its interaction with PD-L1. (A) In … WebJun 2, 2024 · Glycosylation is an important posttranslational modification that covalently …
WebDec 22, 2024 · University of Alabama at Birmingham researcher Jianmei Leavenworth, M.D., Ph.D., has now identified the transcription factor Blimp1 as a new critical regulator of tumor-infiltrating T-reg cells ...
WebOct 12, 2024 · Plasma cells also require a high rate of glucose uptake for glycolysis and …
WebSep 28, 2012 · Primordial germ cells (PGCs) sequentially induce specific genes required for their development. We focused on epigenetic changes that regulate PGC-specific gene expression. mil-1, Blimp1, and Stella are preferentially expressed in PGCs, and their expression is upregulated during PGC differentiation. Here, we first determined DNA … handwriting pen certificateWebPRDM1/BLIMP-1 is a master transcription factor regulating downstream cytokines. It is activated by TLRs and IRF-4, and is crucial in T cell, B cell, and myeloid lineage cell differentiations. As a potent repressor of beta-interferon (IFN-β), BLIMP-1 competes for interferon regulatory factors (IRF) binding sites in the IFN-β promoter due to ... business gcse specification aqaWebMar 1, 2005 · In plasma cells, BLIMP1 (B-lymphocyte-induced maturation protein 1), XBP1 (X-box-binding protein 1) and IRF4 (interferon-regulatory factor 4) are important: they repress the B-cell gene-expression ... handwriting pen palsWebAbstract. The gene encoding the human BLIMP1, prdm1, is located on chromosome 6q21, a locus frequently deleted in lymphoid tumors. BLIMP1 is able to silence its target genes in a context-dependent manner through different mechanisms. BLIMP1 is expressed in both B and T cells, in which it plays important functions. handwriting pens amazonWeb4 Stereoselective Koenigs-Knorr Glycosylation Catalyzed by Urea 来源：ANGEW CHEM INT EDIT( P 1433-7851 E 1521-3773 ) 发表时间: 2016/07 类型：期刊论文 为本人加分：7417.940717 handwriting personality testhttp://www.globalauthorid.com/WebPortal/AuthorView?wd=GAID10160321&rc=6A62E4 handwriting post strokeWebFeb 10, 2011 · Blimp1 (also known as Prdm1) is a pleiotropic transcription factor that plays crucial roles in the differentiation of plasma cells and CD8 + effector T cells. 21-25 In both processes, Blimp1 is required for terminal differentiation and Blimp1 deficiency leads to loss of functional antibody-secreting cells and short-lived cytotoxic T cells. Moreover, in … business gcse topic 1.3