High theophylline levels

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August undefined, 2024

WebApr 1, 2024 · fast, slow, or irregular heartbeat increase in urine volume lightheadedness persistent vomiting pounding or rapid pulse seizures shakiness Get emergency help … WebThe adverse effects of theophylline include: Gastrointestinal disorders such as nausea, vomiting, gastro-oesophageal reflux. Neurological disorders such as tremor, headache, dizziness, central nervous system stimulation, insomnia, and convulsion (rare). Psychiatric disorders such as anxiety.

Theophylline: 15 Answers inc. Side Effects and Toxicity

WebMany factors affect the rate of theophylline metabolism. Concentrations are increased in heart failure, cirrhosis, viral infections and in the elderly, and decreased in smokers, … WebPurpose: To evaluate prospectively whether serum theophylline concentrations of 25 mg/L and greater were predictable (and presumably preventable) by use of basic pharmacokinetic calculations. Design: Prospective study. Patients: Fifty-five patients with a serum theophylline concentration of at least 25.0 mg/L were evaluated initially and if subsequent … iphone 13 sim only deals

Theophylline Extended-Release Tablets

WebFeb 26, 2013 · Theophylline increases histone deacetylase-2 (HDAC2) via inhibition of phosphoinositide-3-kinase-δ (PI3Kδ), which is activated by oxidative stress to phosphorylate and reduce HDAC2. HDAC2 deacetylates core histones that have been acetylated by the histone acetyltransferase (HAT) activity of coactivators, such as CREB-binding protein … WebJun 20, 2024 · High blood sugar (increased thirst, increased urination, hunger, dry mouth, drowsiness, blurred vision, weight loss) ... Low levels of theophylline and caffeine may indicate that the drug has not reached a therapeutic level for the individual tested and there is insufficient drug present to be effective. WebFactor which increase the half life include heart failure, cirrhosis, viral infection and drugs like cimetidine, ciprofloxacin, erythromycin and the oral contraceptive pill. The half life is decreased by smoking, heavy drinking and drugs like phenytoin, carbamazepine, rifampicin and barbiturates. iphone 13 sim swap

National Center for Biotechnology Information

Theophylline Side Effects, Dosage, Uses & More

WebMar 22, 2024 · Theophylline: Although causality has not been established, concurrent use of pentoxifylline with theophylline has resulted in elevated theophylline plasma levels, which may enhance the possibility of adverse effects. Drug-Food Interactions. Interactions with food have not been established. Drug-Herb Interactions WebSixty patients with theophylline toxicity were hospitalized during a 2-year period. Eleven patients had hypercalcemia; their calcium levels returned to normal as theophylline levels … iphone 13 sim slot indiaWebTHEOPHYLLINE AS A BRONCHODILATOR. Traditionally, theophylline was used as a bronchodilator in the treatment of airway disease but, to achieve significant bronchodilatation comparable with that of a β 2 agonist, relatively high plasma concentrations are needed (10–20 mg/l). Theophylline relaxes human airway smooth … iphone 13 sim unlock software

"WebTheophylline levels In most individuals a plasma theophylline of between 10-20mg/litre is required for satisfactory bronchodilation; however, a lower plasma theophylline … " - High theophylline levels

High theophylline levels

Theophylline Toxicity: Background, Pathophysiology, Epidemiology

WebTheophylline in overdose can cause vomiting (which may be severe and intractable), agitation, restlessness, dilated pupils, sinus tachycardia, and hyperglycaemia. More … WebAug 31, 2024 · high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor. Serious side effects may be more likely in older adults. Common side effects …

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WebToxic side effects of elevated theophylline levels range from minor symptoms to life-threatening complications. We investigated the incidence of life-threatening events in … WebHigh-carbohydrate, low-protein diets can increase theophylline activity and side effects. Sustained-release forms of theophylline should be taken on an empty stomach and should not be crushed or chewed. Liquid and non-sustained release theophylline products are best taken on an empty stomach, but they may be taken with food if stomach upset occurs.

WebMar 1, 2024 · At serum Theophylline concentrations > 20 mcg/mL, both the frequency and severity of adverse reactions increase. In general, maintaining peak serum Theophylline concentrations between 10 mcg/mL and 15 … WebJun 27, 2024 · National Center for Biotechnology Information

WebTheophylline interacts with many drugs including: Beta-2 agonists, corticosteroids, diuretics — potentially serious hypokalaemia may result from beta-2 agonist therapy. Check serum … WebIn most individuals, a plasma-theophylline concentration of 10–20 mg/litre (55–110 micromol/litre) is required for satisfactory bronchodilation, although a lower plasma …

WebNo food or liquid (other than water) was allowed for 4 hours after which a standard lunch was served. Mean peak theophylline serum levels (C max) was 6.69 mcg/mL and mean time of peak serum concentration (T ... In patients with high theophylline clearance and half-lives of about 4 to 5 hours, such as children age 1 to 9 years, the trough serum ...

WebNov 3, 2024 · Haemodialysis (if possible charcoal haemoperfusion is the modality of choice). Indications for dialysis include: Theophylline level … iphone 13 sim slot locationWebTheophylline metabolism can be altered by a variety of abnormal physiologic states as well as by exogenous factors. Adult studies demonstrate a significant influence of dietary composition on theophylline biotransformation. ... Compared to the normal diet, high protein diet markedly decreased the half-life, and high carbohydrate diet greatly ... iphone 13 singapore release dateWebFeb 10, 2024 · The reference therapeutic ranges of theophylline are listed below. Reference ranges of theophylline in the treatment asthma vary by age, as follows: Adults: 5-15 µg/mL. Children: 5-10 µg/mL. The... The assessment and diagnosis of exercise-induced bronchoconstriction is made … iphone 13 singapore promotionWebNo food or liquid (other than water) was allowed for 4 hours after which a standard lunch was served. Mean peak theophylline serum levels (C max) was 6.69 mcg/mL and mean … iphone 13 size in mmWebJul 18, 2024 · In high doses, theophylline can cause irritability, tremors and seizures as well as tachycardia, cardiac arrhythmias and sudden death. With the development of safer, better tolerated and more effective inhaled … iphone 13 singapore appleWebJul 11, 2024 · Theophylline levels: Serum theophylline levels should be monitored after initiation of therapy, prior to making dose increases; in the presence of signs or symptoms of toxicity; ... • High blood sugar like confusion, fatigue, increased thirst, increased hunger, passing a lot of urine, flushing, fast breathing, or breath that smells like fruit ... iphone 13 size comparison chart 2021WebOct 4, 2024 · In patients with theophylline overdose who are at high risk for theophylline-induced seizures, e.g., patients with acute overdoses and serum theophylline concentrations > 100 mcg/mL or chronic overdosage in patients > 60 years of age with serum theophylline concentrations > 30 mcg/mL, the need for anticonvulsant therapy should be anticipated ... iphone 13 skin wiqqy