WebUsing 13 C-labeled choline and 13 C-magnetic resonance spectroscopy and western blotting, we show increased de novo choline phospholipid (ChoPL) production and activation of PCYT1A (phosphate cytidylyltransferase 1, choline, alpha), the rate-limiting enzyme of phosphatidylcholine (PtdCho) synthesis, during autophagy. We also discovered that the ... WebProtein target information for 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (Porphyromonas gingivalis W83). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.
UniProt
WebAug 24, 2024 · phosphate cytidylyltransferase 1A Pdss2 decaprenyl diphosphate synthase subunit 2 PEMT phosphatidylethanolamine N-methyltransferase PPi pyrophosphate PRODH proline dehydrogenase PRPP phosphoribosyl pyrophosphate Q oxidized coenzyme Q QH2 reduced coenzyme Q RISP rieske iron-sulfur protein ROS reactive oxygen species SARDH … WebCTP:phosphocholine cytidylyltransferase (CCT) catalyzes a rate-limiting and regulated step in the CDP-choline pathway for the synthesis of phosphatidylcholine (PC) and PC-derived lipids. Control of CCT activity is multi-layered, and includes direct regulation by reversible membrane binding involving … flagyl photosensibilite
De novo phosphatidylcholine synthesis is required for ... - PubMed
WebMar 21, 2024 · PCYT1A (Phosphate Cytidylyltransferase 1A, Choline) is a Protein Coding gene. Diseases associated with PCYT1A include Spondylometaphyseal Dysplasia With Cone-Rod Dystrophy and Leber Plus Disease . Among its related pathways are … Complete information for ERBB2 gene (Protein Coding), Erb-B2 Receptor … LMNA (Lamin A/C) is a Protein Coding gene. Diseases associated with LMNA … MAPK1 (Mitogen-Activated Protein Kinase 1) is a Protein Coding gene. Diseases … http://www.informatics.jax.org/marker/MGI:88557 WebMay 26, 2009 · Although the CCT236 structure reveals elements involved in binding cytidine that are conserved with other members of the cytidylyltransferase superfamily, it also features nonconserved active site residues, His-168 and Tyr-173, that make key interactions with the beta-phosphate of CDP-choline. canon t7 w 18 55mm 75 300mm lens